Product Datasheet
stathmin1(Ab-62) Antibody
Catalog Number: 21518
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P16949
NCBI Protein: NP_001138926.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.60~64 (R-K-S-H-E) derived from Human Stathmin 1.
- appl_detail:
- Predicted MW: 19kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
- other_names:
- STMN1; STN1; stathmin
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total Stathmin 1 protein.
- Background:
- Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
Marklund, U. et al. (1994) Eur. J. Biochem. 225, 53-60.
Gavet, O. et al. (1998) J. Cell Sci. 111, 3333-3346.
Di Paolo, G. et al. (1996) J. Cell. Biol. 133, 1383-1390.
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