CDCP1(CD318) Antibody

Catalog Number:

21479

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9H5V8
NCBI Protein: NP_073753.3

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.828~832( T-Q-E-P-M) derived from Human CDCP1(CD318).

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total CDCP1(CD318) protein.

Applications:

WB

Background:

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N.
Oncogene 20:4402-4408(2001)
Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M.Oncogene 24:5333-5343(2005)
Xia Y., Gil S.G., Carter W.G.J. Cell Biol. 132:727-740(1996)

References:

appl_detail:

Predicted MW: 140kd
Western blotting: 1:500

Datasheet PDF