Product Datasheet  
CDCP1(CD318) Antibody  
Catalog Number: 21479  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9H5V8
    NCBI Protein: NP_073753.3
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.828~832( T-Q-E-P-M) derived from Human CDCP1(CD318).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 140kd
    Western blotting: 1:500
  • other_names：  
  • TRASK; SIMA135;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total CDCP1(CD318) protein.
  • Applications：  
  • WB
  • Background：  
  • May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

    Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N.
    Oncogene 20:4402-4408(2001)
    Bhatt A.S., Erdjument-Bromage H., Tempst P., Craik C.S., Moasser M.M.Oncogene 24:5333-5343(2005)
    Xia Y., Gil S.G., Carter W.G.J. Cell Biol. 132:727-740(1996)



 
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