N-Cadherin(CD325) Antibody

Catalog Number:

21474

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P19022
NCBI Protein: NP_001783.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.800~804(A-I-K-P-V) derived from Human N-Cadherin.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total N-Cadherin protein.

Applications:

WB

Background:

Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density

Bhatt A.S. et.al(2005)Oncogene 24:5333-5343
Salomon D.et.al(1992)J. Cell Sci. 102:7-17
The MGC Project Team(2004)Genome Res. 14:2121-2127

References:

appl_detail:

Predicted MW: 140kd
Western blotting: 1:500

Datasheet PDF