Product Datasheet
N-Cadherin(CD325) Antibody
Catalog Number: 21474
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P19022
NCBI Protein: NP_001783.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.800~804(A-I-K-P-V) derived from Human N-Cadherin.
- appl_detail:
- Predicted MW: 140kd
Western blotting: 1:500
- other_names:
- CDH2; CDCN; NCAD
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total N-Cadherin protein.
- Background:
- Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density
Bhatt A.S. et.al(2005)Oncogene 24:5333-5343
Salomon D.et.al(1992)J. Cell Sci. 102:7-17
The MGC Project Team(2004)Genome Res. 14:2121-2127
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