BMAL1 Antibody

Catalog Number:

21415

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O00327
NCBI Protein: NP_001025443.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total BMAL1 protein.

Applications:

WB

Background:

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins

Lee S,et al. (2010) PLoS One.5(6):e10995.
Wang J,et al. (2010) Biosystems.101(2):136-43.
Jung-Hynes ,et al. (2010) J Pineal Res.49(1):60-8.

References:

appl_detail:

Predicted MW: 69kd
Western blotting: 1:500~1:1000

Datasheet PDF