Product Datasheet
BMAL1 Antibody
Catalog Number: 21415
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O00327
NCBI Protein: NP_001025443.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.
- other_names:
- MOP3; BMAL1c; ARNTL; TIC;
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total BMAL1 protein.
- Background:
ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins
Lee S,et al. (2010) PLoS One.5(6):e10995.
Wang J,et al. (2010) Biosystems.101(2):136-43.
Jung-Hynes ,et al. (2010) J Pineal Res.49(1):60-8.
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