1-832-868-1888
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Catalog Number: |
21307 |
other_names: | CK 8; CK8; CYK8; Cytokeratin endo A; K8 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot: P05787 |
Form of Antibody: |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
Peptide sequence around aa.72~76 (L-L-S-P-L) derived from Human Keratin 8 (CK8). |
Purification: |
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Specificity/Sensitivity: |
The antibody detects endogenous level of total Keratin 8 protein. |
Applications: |
WB IHC IF |
Background: |
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
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References: |
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appl_detail: |
Predicted MW: 55kd |
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