eNOS(Ab-495) Antibody

Catalog Number:

21235

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P29474
NCBI Protein: NP_000594.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.493~497 (K-K-T-F-K) derived from Human eNOS.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total eNOS protein.

Applications:

IF

Background:

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Moreno H Jr.(2008)Breast Cancer Res Treat. 109(1):181-2.
Lorenz M,et al.(2007)FASEB J. May;21(7):1556-64.
Lin HI,et al.(2006)Transplant Proc. Sep;38(7):2203-6.

References:

appl_detail:

Predicted MW: 140kd
Immunofluorescence: 1:100~1:200

Datasheet PDF