Product Datasheet  
eNOS(Ab-495) Antibody  
Catalog Number: 21235  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P29474
    NCBI Protein: NP_000594.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.493~497 (K-K-T-F-K) derived from Human eNOS.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 140kd
    Immunofluorescence: 1:100~1:200
  • other_names：  
  • Constitutive NOS; EC-NOS; ECNOS; NOS3; NOSIII
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total eNOS protein.
  • Applications：  
  • IF
  • Background：  
  • Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

    Moreno H Jr.(2008)Breast Cancer Res Treat. 109(1):181-2.
    Lorenz M,et al.(2007)FASEB J. May;21(7):1556-64.
    Lin HI,et al.(2006)Transplant Proc. Sep;38(7):2203-6.



 
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