c-Kit(Ab-721) Antibody

Catalog Number:

21232

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11362
NCBI Protein: NP_000213.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.719~723 (N-E-Y-M-D) derived from Human c-Kit.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total c-Kit protein.

Applications:

WB

Background:

This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

Kimura W,et al.(2007)Hepatogastroenterology.54(80):2203-8.
Naeem M,et al.(2002)Hum Pathol. 33(12):1182-7.
Jankulovski N, et al.(2006)Prilozi. 27(2):59-70.

References:

appl_detail:

Predicted MW: 145kd
Western blotting: 1:500~1:1000

Datasheet PDF