Product Datasheet  
c-Kit(Ab-721) Antibody  
Catalog Number: 21232  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: P11362
    NCBI Protein: NP_000213.1
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen:  
  • Peptide sequence around aa.719~723 (N-E-Y-M-D) derived from Human c-Kit.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 145kd
    Western blotting: 1:500~1:1000
  • other_names:  
  • KIT; CD117; SCFR; PBT;
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity:  
  • The antibody detects endogenous level of total c-Kit protein.
  • Applications:  
  • WB
  • Background:  
  • This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

    Kimura W,et al.(2007)Hepatogastroenterology.54(80):2203-8.
    Naeem M,et al.(2002)Hum Pathol. 33(12):1182-7.
    Jankulovski N, et al.(2006)Prilozi. 27(2):59-70.



 
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