1-832-868-1888
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Catalog Number: |
21231 |
other_names: | FGFBR; FGFR-1; FGR1; FLG; FLT2 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot: P08581 |
Form of Antibody: |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
Peptide sequence around aa.152~156 (A-P-Y-W-T) derived from Human FGF Receptor 1. |
Purification: |
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Specificity/Sensitivity: |
The antibody detects endogenous level of total FGF Receptor 1 protein. |
Applications: |
WB |
Background: |
FGF encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
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References: |
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appl_detail: |
Predicted MW: 145kd |
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