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Home > products > FGF Receptor 1(Ab-154) Antibody

FGF Receptor 1(Ab-154) Antibody

Catalog Number:

21231
other_names: FGFBR; FGFR-1; FGR1; FLG; FLT2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P08581
NCBI Protein: NP_001167534.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.152~156 (A-P-Y-W-T) derived from Human FGF Receptor 1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total FGF Receptor 1 protein.

Applications:

WB

Background:

FGF encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Wu X,et al.(2001)Acta Obstet Gynecol Scand.80(6):497-504.
Faraone D,et al.(2006) Blood. 107(5):1896-902.
Claus P,et al.(2004)Neurosci Lett.360(3):117-20.

References:

appl_detail:

Predicted MW: 145kd
Western blotting: 1:500~1:1000

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