Product Datasheet  
FGF Receptor 1(Ab-154) Antibody  
Catalog Number: 21231  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P08581
    NCBI Protein: NP_001167534.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.152~156 (A-P-Y-W-T) derived from Human FGF Receptor 1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 145kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • FGFBR; FGFR-1; FGR1; FLG; FLT2
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total FGF Receptor 1 protein.
  • Applications：  
  • WB
  • Background：  
  • FGF encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

    Wu X,et al.(2001)Acta Obstet Gynecol Scand.80(6):497-504.
    Faraone D,et al.(2006) Blood. 107(5):1896-902.
    Claus P,et al.(2004)Neurosci Lett.360(3):117-20.



 
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