ATRIP (Phospho-Ser224) Antibody

Catalog Number:

12130

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q8WXE1;
NCBI Gene#:84126

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 224 (H-V-S(p)-P-R) derived from Human ATRIP.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of ATRIP only when phosphorylated at serine 224.

Applications:

WB IHC

Background:

Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF