Product Datasheet  
ATRIP (Phospho-Ser224) Antibody  
Catalog Number: 12130  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q8WXE1;
    NCBI Gene#:84126
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 224 (H-V-S(p)-P-R) derived from Human ATRIP.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • ATIP; ATM and Rad3 related interacting protein; ATR-interacting protein
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of ATRIP only when phosphorylated at serine 224.
  • Applications：  
  • WB IHC
  • Background：  
  • Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.



 
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