p70 S6 Kinase beta (Phospho-Ser423) Antibody

Catalog Number:

12066

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UBS0;
NCBI Gene#: 6199;
NCBI Protein#: NP_003943.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 423 (P-V-S(p)-P-L) derived from Human p70 S6 Kinase beta.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of p70 S6 Kinase beta only when phosphorylated at Serine 423.

Applications:

WB

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B).

References:

appl_detail:

Predicted MW: 53kd
Western blotting: 1:500~1:1000

Datasheet PDF