Product Datasheet
p70 S6 Kinase beta (Phospho-Ser423) Antibody
Catalog Number: 12066
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UBS0;
NCBI Gene#: 6199;
NCBI Protein#: NP_003943.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 423
(P-V-S(p)-P-L) derived from Human p70 S6 Kinase beta.
- appl_detail:
- Predicted MW: 53kd
Western blotting: 1:500~1:1000
- other_names:
- KLS, SRK, S6K2, STK14B, p70S6Kb
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of p70 S6 Kinase beta only when phosphorylated at Serine 423.
- Background:
- This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B).
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