Product Datasheet  
p70 S6 Kinase beta (Phospho-Ser423) Antibody  
Catalog Number: 12066  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9UBS0;
    NCBI Gene#: 6199;
    NCBI Protein#: NP_003943.2
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Peptide sequence around phosphorylation site of Serine 423 (P-V-S(p)-P-L) derived from Human p70 S6 Kinase beta.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 53kd
    Western blotting: 1:500~1:1000
  • other_names:  
  • KLS, SRK, S6K2, STK14B, p70S6Kb
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity:  
  • The antibody detects endogenous level of p70 S6 Kinase beta only when phosphorylated at Serine 423.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B).



 
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