Calcium Sensing Receptor (Phospho-Thr888) Antibody

Catalog Number:

12041

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P41180;
NCBI Gene#: 846;
NCBI Protein#: NP_000379.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Threonine 888 (R-A-T(p)-L-R) derived from Human Calcium Sensing Receptor.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of Calcium Sensing Receptor only when phosphorylated at Threonine 888.

Applications:

WB

Background:

Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

References:

appl_detail:

Predicted MW: 140kd
Western blotting: 1:500~1:1000

Datasheet PDF