Product Datasheet
Calcium Sensing Receptor (Phospho-Thr888) Antibody
Catalog Number: 12041
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P41180;
NCBI Gene#: 846;
NCBI Protein#: NP_000379.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Threonine 888
(R-A-T(p)-L-R) derived from Human Calcium Sensing Receptor.
- appl_detail:
- Predicted MW: 140kd
Western blotting: 1:500~1:1000
- other_names:
- CAR, FHH, FIH, HHC, EIG8
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of Calcium Sensing Receptor only when phosphorylated at Threonine 888.
- Background:
- Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
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