Dynamin-1 (Phospho-Ser774) Antibody

Catalog Number:

12005

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q05193;
NCBI Gene#: 1759;
NCBI Protein#: NP_001005336.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 774 (R-R-S(p)-P-T) derived from Dynamin-1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of Dynamin-1 only when phosphorylated at Serine 774.

Applications:

WB

Background:

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

References:

appl_detail:

Predicted MW: 97kd
Western blotting: 1:500~1:1000

Datasheet PDF