Product Datasheet
Dynamin-1 (Phospho-Ser774) Antibody
Catalog Number: 12005
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q05193;
NCBI Gene#: 1759;
NCBI Protein#: NP_001005336.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of serine 774
(R-R-S(p)-P-T) derived from Dynamin-1.
- appl_detail:
- Predicted MW: 97kd
Western blotting: 1:500~1:1000
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of Dynamin-1 only when phosphorylated at Serine 774.
- Background:
- Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
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