NMDAR2B (Phospho-Tyr1336) Antibody

Catalog Number:

11959

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13224;
NCBI Gene#: 2904;
NCBI Protein#: NP_000825.2

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine1336 (S-P-Y(p)-A-H) derived from Human NMDAR2B.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of NMDAR2B only when phosphorylated at tyrosine 1336.

Applications:

WB

Background:

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Morel V, et al. (2013) Eur J Pharmacol 721, 382-90. Peng HY, et al. (2010)Am J Physiol Renal Physiol 298, F109-17. Wu HY, et al. (2007) J Biol Chem 282, 20075-87.

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF