Product Datasheet  
NMDAR2B (Phospho-Tyr1336) Antibody  
Catalog Number: 11959  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q13224;
    NCBI Gene#: 2904;
    NCBI Protein#: NP_000825.2
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Tyrosine1336 (S-P-Y(p)-A-H) derived from Human NMDAR2B.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • GRIN2B; hNR3; NME2; NR3; NMDE2
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of NMDAR2B only when phosphorylated at tyrosine 1336.
  • Applications：  
  • WB
  • Background：  

  • NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

    Morel V, et al. (2013) Eur J Pharmacol 721, 382-90. Peng HY, et al. (2010)Am J Physiol Renal Physiol 298, F109-17. Wu HY, et al. (2007) J Biol Chem 282, 20075-87.




 
© Signalway Biotechnology All Rights Reserved.