JAK2 (Phospho-Tyr931) Antibody

Catalog Number:

11932

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60674;
NCBI Gene#: 3717;
NCBI Protein#: NP_004963.1

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 931 (M-E-Y(p)-L-P) derived from Human JAK2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of JAK2 only when phosphorylated at tyrosine 931.

Applications:

WB

Background:

Plays a role in leptin signaling and control of body weight

Matsuda T, et al. (2004)Biochem Biophys Res Commun 325, 586-94
Rikova K, et al. (2007)Cell 131, 1190-203

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF