Product Datasheet  
JAK2 (Phospho-Tyr931) Antibody  
Catalog Number: 11932  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O60674;
    NCBI Gene#: 3717;
    NCBI Protein#: NP_004963.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 931 (M-E-Y(p)-L-P) derived from Human JAK2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • JAK-2; JAK2; Janus kinase 2; kinase Jak2;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of JAK2 only when phosphorylated at tyrosine 931.
  • Applications：  
  • WB
  • Background：  

  • Plays a role in leptin signaling and control of body weight

    Matsuda T, et al. (2004)Biochem Biophys Res Commun 325, 586-94
    Rikova K, et al. (2007)Cell 131, 1190-203




 
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