FGFR4 (Phospho-Tyr642) Antibody

Catalog Number:

11836

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P22455;
NCBI Gene#: 2264;
NCBI Protein#: NP_002002.3.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 642(I-D-Y(p)-Y-K) derived from Human FGFR4 .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of FGFR4 only when phosphorylated at tyrosine 642.

Applications:

WB

Background:

Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

Partanen J.M., EMBO J. 10:1347-1354(1991) [PubMed: 1709094].
Ron D., J. Biol. Chem. 268:5388-5394(1993) [PubMed: 7680645].
Takaishi S.,Biochem. Biophys. Res. Commun. 267:658-662(2000) [PubMed: 10631118].

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF