Product Datasheet  
FGFR4 (Phospho-Tyr642) Antibody  
Catalog Number: 11836  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P22455;
    NCBI Gene#: 2264;
    NCBI Protein#: NP_002002.3.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 642(I-D-Y(p)-Y-K) derived from Human FGFR4 .
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • FGFR-4; CD_antigen=CD334; Fibroblast growth factor receptor 4; EC=2.7.10.1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of FGFR4 only when phosphorylated at tyrosine 642.
  • Applications：  
  • WB
  • Background：  

  • Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

    Partanen J.M., EMBO J. 10:1347-1354(1991) [PubMed: 1709094].
    Ron D., J. Biol. Chem. 268:5388-5394(1993) [PubMed: 7680645].
    Takaishi S.,Biochem. Biophys. Res. Commun. 267:658-662(2000) [PubMed: 10631118].




 
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