CNOT2 (Phospho-Ser101) Antibody

Catalog Number:

11810

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NZN8;
NCBI Gene#: 4848;
NCBI Protein#: NP_001186231.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine101(S-L-S(p)-Q-G) derived from Human CNOT2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of CNOT2 only when phosphorylated at serine 101.

Applications:

IHC

Background:

The CCR4-NOT complex functions as general transcription regulation complex. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. 5 isoforms of the human protein are produced by alternative splicing.

Albert T.K., Nucleic Acids Res. 28:809-817(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF