Product Datasheet  
CNOT2 (Phospho-Ser101) Antibody  
Catalog Number: 11810  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9NZN8;
    NCBI Gene#: 4848;
    NCBI Protein#: NP_001186231.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine101(S-L-S(p)-Q-G) derived from Human CNOT2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100

  • other_names：  
  • NOT2H; CDC36; CNOT2; HSPC131;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of CNOT2 only when phosphorylated at serine 101.
  • Applications：  
  • IHC
  • Background：  

  • The CCR4-NOT complex functions as general transcription regulation complex. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. 5 isoforms of the human protein are produced by alternative splicing.

    Albert T.K., Nucleic Acids Res. 28:809-817(2000).
    Zhang Q.-H., Genome Res. 10:1546-1560(2000).
    Ota T., Nat. Genet. 36:40-45(2004).




 
© Signalway Biotechnology All Rights Reserved.