APLP2 (Phospho-Tyr755) Antibody

Catalog Number:

11784

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q06481;
NCBI Gene#: 334;
NCBI Protein#: NP_001633.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) derived from Human APLP2.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755

Applications:

IHC

Background:

APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box).

Sprecher C.A., Biochemistry 32:4481-4486(1993).
Wasco W., Nat. Genet. 5:95-99(1993).
von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF