Product Datasheet  
APLP2 (Phospho-Tyr755) Antibody  
Catalog Number: 11784  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q06481;
    NCBI Gene#: 334;
    NCBI Protein#: NP_001633.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) derived from Human APLP2.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100

  • other_names：  
  • Amyloid protein homolog ; Amyloid-like protein 2 precursor; APP2; APPH; CDEI-box binding protein
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755
  • Applications：  
  • IHC
  • Background：  

  • APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box).

    Sprecher C.A., Biochemistry 32:4481-4486(1993).
    Wasco W., Nat. Genet. 5:95-99(1993).
    von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).




 
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