Paxillin (Phospho-Ser178) Antibody

Catalog Number:

11773

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49023;
NCBI Gene#: 5829;
NCBI Protein#: NP_001074324.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 178(A-L-S(p)-P-L) derived from Human Paxillin.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The Antibody detects endogenous levels of Paxillin only when phosphorylated at Ser178.

Applications:

WB

Background:

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047(1995)
Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF