Product Datasheet  
Paxillin (Phospho-Ser178) Antibody  
Catalog Number: 11773  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P49023;
    NCBI Gene#: 5829;
    NCBI Protein#: NP_001074324.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 178(A-L-S(p)-P-L) derived from Human Paxillin.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • Paxillin; PXN;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The Antibody detects endogenous levels of Paxillin only when phosphorylated at Ser178.
  • Applications：  
  • WB
  • Background：  

  • Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

    S Chen L.B., Griffin J.D. J. Biol. Chem. 270:5039-5047(1995)
    Bell G.I.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases




 
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