OSR1 (Phospho-Thr185) Antibody

Catalog Number:

11746

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95747;
NCBI Gene#: 9943;
NCBI Protein#: NP_005100.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.

Applications:

WB IHC

Background:

Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress

Tamari M., J. Hum. Genet. 44:116-120(1999).
Kikuno R., DNA Res. 6-197-205(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Datasheet PDF