Product Datasheet  
OSR1 (Phospho-Thr185) Antibody  
Catalog Number: 11746  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O95747;
    NCBI Gene#: 9943;
    NCBI Protein#: NP_005100.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100

  • other_names：  
  • OXSR1; kinase OSR1; Oxidative-stress responsive 1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of OSR1 only when phosphorylated at threonine 185.
  • Applications：  
  • WB IHC
  • Background：  

  • Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress

    Tamari M., J. Hum. Genet. 44:116-120(1999).
    Kikuno R., DNA Res. 6-197-205(1999).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).




 
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