FER (Phospho-Tyr402) Antibody

Catalog Number:

11730

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P16591;
NCBI Gene#: 2241;
NCBI Protein#: NP_005237.2.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 402(V-N-Y(p)-E-E) derived from Human FER .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of FER only when phosphorylated at tyrosine 402.

Applications:

WB IHC

Background:

Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.

Hao Q.-L., Mol. Cell. Biol. 9:1587-1593(1989).
Lee S.-T., Oncogene 8:3403-3410(1993).
Krolewski J.J., Oncogene 5:277-282(1990).

References:

appl_detail:

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Datasheet PDF