Product Datasheet
FER (Phospho-Tyr402) Antibody
Catalog Number: 11730
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P16591;
NCBI Gene#: 2241;
NCBI Protein#: NP_005237.2.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 402(V-N-Y(p)-E-E) derived from Human FER .
- other_names:
- FER; FERT2; TYK3; p94-FER;
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of FER only when phosphorylated at tyrosine 402.
- Background:
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
Hao Q.-L., Mol. Cell. Biol. 9:1587-1593(1989).
Lee S.-T., Oncogene 8:3403-3410(1993).
Krolewski J.J., Oncogene 5:277-282(1990).
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