IL-2Rβ/CD122 (Phospho-Tyr364) Antibody

Catalog Number:

11697

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P14784;
NCBI Gene#: 3560;
NCBI Protein#: NP_000869.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 364(Q-G-Y(p)-F-F) derived from Human IL-2Rβ/CD122 .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of IL-2Rβ/CD122 only when phosphorylated at tyrosine 364.

Applications:

WB

Background:

Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Hatakeyama M., Science 244:551-556(1989).
Dunham I., Nature 402:489-495(1999).
Mulloy J.C., J. Virol. 70:3599-3605(1996)

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF