Product Datasheet
IL-2Rβ/CD122 (Phospho-Tyr364) Antibody
Catalog Number: 11697
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P14784;
NCBI Gene#: 3560;
NCBI Protein#: NP_000869.1.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 364(Q-G-Y(p)-F-F) derived from Human IL-2Rβ/CD122 .
- other_names:
- CD122 antigen; P70-75; IL-2 receptor; IL-2R beta;
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of IL-2Rβ/CD122 only when phosphorylated at tyrosine 364.
- Background:
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Hatakeyama M., Science 244:551-556(1989).
Dunham I., Nature 402:489-495(1999).
Mulloy J.C., J. Virol. 70:3599-3605(1996)
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