GATA2 (Phospho-Ser401) Antibody

Catalog Number:

11691

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P23769;
NCBI Gene#: 2624;
NCBI Protein#: NP_001139133.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 401(K-M-S(p)-N-K) derived from Human GATA2 .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of GATA2 only when phosphorylated at serine 401.

Applications:

WB

Background:

Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.

Lee M.-E., J. Biol. Chem. 266:16188-16192(1991).
Dorfman D.M., J. Biol. Chem. 267:1279-1285(1992).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF