Product Datasheet
GATA2 (Phospho-Ser401) Antibody
Catalog Number: 11691
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P23769;
NCBI Gene#: 2624;
NCBI Protein#: NP_001139133.1.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 401(K-M-S(p)-N-K) derived from Human GATA2 .
- other_names:
- GATA binding protein 2; Endothelial transcription factor GATA-2;
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of GATA2 only when phosphorylated at serine 401.
- Background:
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.
Lee M.-E., J. Biol. Chem. 266:16188-16192(1991).
Dorfman D.M., J. Biol. Chem. 267:1279-1285(1992).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
© Signalway Biotechnology All Rights Reserved.