JAK2 (Phospho-Tyr570) Antibody

Catalog Number:

11663

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60674;
NCBI Gene#: 3717;
NCBI Protein#: NP_004963.1.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 570(G-D-Y(p)-G-Q) derived from Human JAK2 .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.

Applications:

WB

Background:

Plays a role in leptin signaling and control of body weight.

Saltzman A., Biochem. Biophys. Res. Commun. 246:627-633(1998).
Dalal I., Blood 91:844-851(1998).
Peeters P., Blood 90:2535-2540(1997).

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF