Product Datasheet  
JAK2 (Phospho-Tyr570) Antibody  
Catalog Number: 11663  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O60674;
    NCBI Gene#: 3717;
    NCBI Protein#: NP_004963.1.
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Peptide sequence around phosphorylation site of tyrosine 570(G-D-Y(p)-G-Q) derived from Human JAK2 .
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500~1:1000

  • other_names:  
  • JAK2; Janus kinase 2; kinase Jak2;
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity:  
  • The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.
  • Applications:  
  • WB
  • Background:  
  • Plays a role in leptin signaling and control of body weight.

    Saltzman A., Biochem. Biophys. Res. Commun. 246:627-633(1998).
    Dalal I., Blood 91:844-851(1998).
    Peeters P., Blood 90:2535-2540(1997).




 
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