Product Datasheet
JAK2 (Phospho-Tyr570) Antibody
Catalog Number: 11663
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60674;
NCBI Gene#: 3717;
NCBI Protein#: NP_004963.1.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 570(G-D-Y(p)-G-Q) derived from Human JAK2 .
- other_names:
- JAK2; Janus kinase 2; kinase Jak2;
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of JAK2 only when phosphorylated at tyrosine 750.
- Background:
Plays a role in leptin signaling and control of body weight.
Saltzman A., Biochem. Biophys. Res. Commun. 246:627-633(1998).
Dalal I., Blood 91:844-851(1998).
Peeters P., Blood 90:2535-2540(1997).
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