Synapsin(phospho-Ser549) Antibody

Catalog Number:

11568

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O88935
NCBI Protein: NP_038708.3

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 549(P-A-S(p)-P-S)derived from Rat Synapsin

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of Synapsin only when phosphorylated at serine 549.

Applications:

WB

Background:

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level

Greengard, P. (1987) Mol Neurobiol 1, 81-119.
Hosaka, M. et al. (1999) Neuron 24, 377-87.

References:

appl_detail:

Predicted MW: 78kd
Western blotting: 1:500~1:1000

Datasheet PDF