Product Datasheet  
Synapsin(phospho-Ser549) Antibody  
Catalog Number: 11568  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O88935
    NCBI Protein: NP_038708.3
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 549(P-A-S(p)-P-S)derived from Rat Synapsin
  • reactivity：  
  • Hu Rt Ms
  • appl_detail：  

  • Predicted MW: 78kd
    Western blotting: 1:500~1:1000

  • other_names：  
  • Syn-1; synapsin I;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Synapsin only when phosphorylated at serine 549.
  • Applications：  
  • WB
  • Background：  

  • Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level

    Greengard, P. (1987) Mol Neurobiol 1, 81-119.
    Hosaka, M. et al. (1999) Neuron 24, 377-87.




 
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