CD70 Rabbit mAb

Catalog Number:

78348

Amount:

100μg

Price:

$318

Swiss-Prot No:

P32970

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human CD70.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF