Product Datasheet  
CD70 Rabbit mAb  
Catalog Number: 78348  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • P32970
  • Form of Antibody：  
  • Storage：  
  • Store at 4℃ (regular) or -20℃ (long term). Avoid freeze |Buffer: PBS with 0.02% thimerosal,pH7.4.
  • Immunogen：  
  • Recombinant protein of human CD70.
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.



 
© Signalway Biotechnology All Rights Reserved.