1-832-868-1888
order@swbio.com
Catalog Number: |
28297 |
other_names: | |
Amount: |
100μg |
calculated_mw: | |
host_species: | |
Price: |
$319 |
Swiss-Prot No: |
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Form of Antibody: |
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Storage/Stability: |
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Immunogen: |
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Purification: |
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Specificity/Sensitivity: |
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Applications: |
FC |
Background: |
CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. |
References: |
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appl_detail: |
Format: APC Vol.per.Test: 20 μl to 5 μl per test Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA |
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