Product Datasheet
Mouse anti-Human CD80, APC Conjugated mAb
Catalog Number: 28297
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
- reactivity:
- Human, Not yet tested in other species.
- appl_detail:
Format: APC
Vol.per.Test: 20 μl to 5 μl per test
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
- Background:
CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
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