Product Datasheet  
Mouse anti-Human CD80, APC Conjugated mAb  
Catalog Number: 28297  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Form of Antibody:  
  • Storage:  
  • Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
  • Immunogen:  
  • reactivity:  
  • Human, Not yet tested in other species.
  • appl_detail:  
  • Format: APC

    Vol.per.Test: 20 μl to 5 μl per test

    Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

  • other_names:  
  • Purification:  
  • Specificity:  
  • Applications:  
  • FC
  • Background:  
  • CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. 




 
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